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Under Construction - Dr. Deborha Toiber BGU

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Manage episode 274091745 series 2668663
内容由Gil marorm提供。所有播客内容(包括剧集、图形和播客描述)均由 Gil marorm 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Imagine a substances inside the body with the ability to repair it's own DNA damage, sounds like science fictions? join me and Dr. Debi Toiber and discover the wonders of Sirt6 enzyme. Dr. Toiber lab discovered that SIRT6 is an enzyme that recognizes DNA damage and allows its repair, SIRT6 acts as a sensor of Double strand breaks, and in its absence DNA damage accumulates faster, leading to diseases. In our chat we have touched how her lab is working to understand better the relationship between the aging process and Sirt6 enzyme and how it is behaving in the body, those efforts and their animal model can open a window of opportunity for the study of sporadic (age related) neurodegeneration and point us to future novel treatments.

  continue reading

18集单集

Artwork
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Manage episode 274091745 series 2668663
内容由Gil marorm提供。所有播客内容(包括剧集、图形和播客描述)均由 Gil marorm 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Imagine a substances inside the body with the ability to repair it's own DNA damage, sounds like science fictions? join me and Dr. Debi Toiber and discover the wonders of Sirt6 enzyme. Dr. Toiber lab discovered that SIRT6 is an enzyme that recognizes DNA damage and allows its repair, SIRT6 acts as a sensor of Double strand breaks, and in its absence DNA damage accumulates faster, leading to diseases. In our chat we have touched how her lab is working to understand better the relationship between the aging process and Sirt6 enzyme and how it is behaving in the body, those efforts and their animal model can open a window of opportunity for the study of sporadic (age related) neurodegeneration and point us to future novel treatments.

  continue reading

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