Cutting-Edge Concepts in HIV Care: Long-Acting Therapies

CCO Infectious Disease Podcast

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1+ y ago 19:31

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In this episode, Paul E. Sax, MD, discusses long-acting (LA) injectables for HIV treatment, including:

Guidance on the use of LA cabotegravir (CAB) + rilpivirine (RPV)
Risk factors for virologic failure of LA CAB + RPV
The ATLAS-2M study
Combined clinical trials of LA CAB + RPV
Practical considerations for LA CAB + RPV
Implementation of LA CAB + RPV
Switching to LA CAB + RPV without an oral lead-in, including a discussion of the FLAIR extension study
Supporting candidates for LA antiretroviral therapy (ART)
Discussion of an implementation study of LA CAB + RPV in patients with challenges to oral ART adherence in San Francisco
Future LA ART
The investigational LA HIV capsid inhibitor lenacapavir (LEN)
LEN resistance from the CAPELLA and CALIBRATE studies
LEN injection-site reactions in the CAPELLA and CALIBRATE studies

Presenter:

Paul E. Sax, MD
Clinical Director
HIV Program and Division of Infectious Diseases
Brigham and Women’s Hospital
Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Link to full program:
https://bit.ly/3VIsDTg

Follow along with the slides at:
http://bit.ly/3Gh9AKG

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