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Novel Cancer Therapeutic Targets and Inhibits Nuclear Beta-Catenin in Desmoid Tumor Study with Rahul Aras Iterion Therapeutics
Manage episode 275412415 series 99915
内容由Karen Jagoda提供。所有播客内容（包括剧集、图形和播客描述）均由 Karen Jagoda 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品，您可以按照此处概述的流程进行操作https://zh.player.fm/legal。
Rahul Aras, CEO, Iterion Therapeutics, describes their lead product Tegavivint, a potent selective inhibitor of nuclear beta-catenin, a high-value oncology target because of its role in cell proliferation, differentiation, immune evasion and other aspects of cancer development. An early clinical study in patients with the rare disease Desmoid tumors has showed that their tumor stabilized and reversed in size. Progress is being driven by recent understanding of the role of TBL1 in driving oncogenic activity of beta-catenin.
#IterionTherapeutics #Tegavivint #cancer #DesmoidTumors #nuclearbetacatenin #TBL1
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Manage episode 275412415 series 99915
内容由Karen Jagoda提供。所有播客内容（包括剧集、图形和播客描述）均由 Karen Jagoda 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品，您可以按照此处概述的流程进行操作https://zh.player.fm/legal。
Rahul Aras, CEO, Iterion Therapeutics, describes their lead product Tegavivint, a potent selective inhibitor of nuclear beta-catenin, a high-value oncology target because of its role in cell proliferation, differentiation, immune evasion and other aspects of cancer development. An early clinical study in patients with the rare disease Desmoid tumors has showed that their tumor stabilized and reversed in size. Progress is being driven by recent understanding of the role of TBL1 in driving oncogenic activity of beta-catenin.
#IterionTherapeutics #Tegavivint #cancer #DesmoidTumors #nuclearbetacatenin #TBL1
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类似 Empowered Patient Podcast 的节目
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continue reading
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continue reading
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…
continue reading
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…
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