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Ep. 94: “Engineering Immunity” Featuring Dr. Lili Yang

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Manage episode 453525704 series 2895470
内容由The Immunology Podcast提供。所有播客内容(包括剧集、图形和播客描述)均由 The Immunology Podcast 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Guest:

Dr. Lili Yang is a Professor of Microbiology, Immunology, and Molecular Genetics at the University of California, Los Angeles. Her research centers on deciphering the molecular mechanisms regulating anti-cancer immune responses, exploiting knowledge to develop novel immunotherapies for treating cancer, and translating these new cancer immunotherapies from bench to bedside. She talks about engineering off-the-shelf immunotherapies to fight cancer and generating CAR-NKT cells from hematopoietic stem and progenitor cells. She also discusses the role of serotonin and how SSRIs can affect cancer therapy efficacy.

Featured Products and Resources:

The Immunology Science Round Up

Preventing Apoptosis – Apoptosis inhibition by NLRP3 activators is due to their effects on mitochondria rather than inflammasome activation.

SARS-CoV-2 Spike Proteins in the Brain – SARS-CoV-2 spike protein persists in the skull-meninges-brain axis in COVID-19 patients.

CAR T to Protect Transplanted Beta Cells – hPSCs and Tregs can be co-engineered to protect hPSC-derived cells from immune rejection upon transplantation.

Endogenous Retrovirus Antibodies – An antibody produced by endogenous retrovirus-reactive B cells recognized glycans of a broad range of enveloped viruses.

Image courtesy of Dr. Lili Yang

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Never miss updates about new episodes.

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  continue reading

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icon分享
 
Manage episode 453525704 series 2895470
内容由The Immunology Podcast提供。所有播客内容(包括剧集、图形和播客描述)均由 The Immunology Podcast 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Guest:

Dr. Lili Yang is a Professor of Microbiology, Immunology, and Molecular Genetics at the University of California, Los Angeles. Her research centers on deciphering the molecular mechanisms regulating anti-cancer immune responses, exploiting knowledge to develop novel immunotherapies for treating cancer, and translating these new cancer immunotherapies from bench to bedside. She talks about engineering off-the-shelf immunotherapies to fight cancer and generating CAR-NKT cells from hematopoietic stem and progenitor cells. She also discusses the role of serotonin and how SSRIs can affect cancer therapy efficacy.

Featured Products and Resources:

The Immunology Science Round Up

Preventing Apoptosis – Apoptosis inhibition by NLRP3 activators is due to their effects on mitochondria rather than inflammasome activation.

SARS-CoV-2 Spike Proteins in the Brain – SARS-CoV-2 spike protein persists in the skull-meninges-brain axis in COVID-19 patients.

CAR T to Protect Transplanted Beta Cells – hPSCs and Tregs can be co-engineered to protect hPSC-derived cells from immune rejection upon transplantation.

Endogenous Retrovirus Antibodies – An antibody produced by endogenous retrovirus-reactive B cells recognized glycans of a broad range of enveloped viruses.

Image courtesy of Dr. Lili Yang

Subscribe to our newsletter!

Never miss updates about new episodes.

Subscribe
  continue reading

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