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There is no personalized medicine without a diagnostic test to help in the process. The Promise of Personalized Medicine is a podcast that explores the process of creating more personalized medicine and the Medical Directors who ensure that the right care is being delivered to us all. Season 1 will focus on understanding best practices by using the Blueprint of Success format as a template for labs to use when trying to get their novel diagnostic test approved by health plans. This is The Pr ...
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On this podcast leading scientist, clinicians and entrepreneurs share their thoughts on the progress of personalized medicine. With our guests, we discuss new technologies for targeted treatments and diagnostics, their benefits for patients and clinicians and related implementation challenges.
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Today we sit with Tyler O’Malley, an expert in the evolving fields of personalized and precision medicine, to explore how advancements in diagnostics are transforming patient care. Tyler shares his vision for healthcare that shifts away from broad-based disease management toward more individualized treatment, especially in challenging fields like a…
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Imagine going to the doctor and knowing your treatment is designed just for you—tailored to your unique biology, lifestyle, and even your genetic code. That’s the promise of personalized medicine. But with all the advancements in precision healthcare, are we truly getting more personalized care, or are we just layering new technologies onto old pra…
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The fight for reimbursement often feels like navigating a maze. From lengthy appeals to prior authorizations, labs and healthcare providers must balance innovation with complex payer policies. But what if this process could be less adversarial, more collaborative, and streamlined with the help of cutting-edge technology? Our guest today is Tom Cron…
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In personalized medicine, where data, technology, and patient care converge, success depends on embracing change and collaboration. As our guest puts it, 'At the end of the day, it's all about patient care. So if we have to make some changes in order to make a positive change for them, let's do that.' Today’s guest is Rennie Quarles, Sr. Director B…
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Picture this: You walk into a doctor's office, and instead of a one-size-fits-all prescription, you're handed a treatment plan designed specifically for your genetic makeup. This isn't science fiction; it's the groundbreaking promise of personalized medicine, where cutting-edge technology meets the intricacies of human biology to provide precise an…
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Personalized medicine still has so much potential. With the need for greater adoption and further advancement becoming more apparent, this conversation is necessary. Today's guest is Dr. Sandy Milligan, the President of Research & Development, Laboratory Operations, IT and HR at Aspira Women’s Health. Dr. Milligan explains the nuances of personaliz…
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Clinical research plays a critical role in advancing medical treatments. Today's guest is Dr. Wren Gregory, the Director of Laboratory Operations and Clinical Research at Precision Genetics. Join us as Dr. Wren describes her responsibilities in overseeing lab documentation, compliance, and team mentorship, ensuring smooth operations at Precision Ge…
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Progress and transformation–are two words we definitely want to be associated with our US Healthcare. Today’s guest, Beth Davis, addresses the significant strides made in digital healthcare and smart technologies, ranging from wearable devices to implantable devices that monitor vital signs and manage chronic conditions like diabetes. She emphasize…
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The tables are turned on our regular host, Perry Dimas, and this week–he becomes the guest! Our Producer, Angela, takes the hosting seat and asks Perry all those questions you’ve been wanting to know. Questions like: What are YOUR thoughts on Personalized Medicine? What has made Season 2 special, so far? What is the newest piece of information that…
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Our DNA holds the keys to understanding our health and well-being. Our guest today is Jill Davies, CEO at Genome Medical. She emphasizes the crucial role of genetic counselors in deciphering complex genetic information for individuals, offering tailored guidance on healthcare decisions. Jill introduces the concept of genetic counseling assistants, …
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Coding in the world of medical tests and personalized medicine may not be the most scintillating topic, but it's a critical puzzle piece that can make or break the seamless delivery of healthcare services. Our guest today is Dr. James Almas, the National Medical Director for Clinical Effectiveness at Labcorp, who provides an in-depth exploration of…
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The goal of personalized medicine is to pinpoint the most effective treatments and reduce the morbidity and toxicity associated with unnecessary therapies. One of the major challenges in the field is securing reimbursement for personalized medicine services. While Medicare often leads the way in adopting new approaches, other payers vary in their c…
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While the healthcare industry innovates at an often unprecedented rate, payors grapple with the complexities of implementation and sustainability. From the payors vantage point, there is both excitement and trepidation surrounding personalized medicine’s rapid evolution. Today’s guest, Suzanne Belinson emphasizes the critical role of diagnostics co…
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Using genomics or other biomarkers to improve health care is the essence of Personalized Medicine according to today’s guest, Dr. Bruce Quinn. Moving forward with novel diagnostic testing could prove challenging for a variety of reasons, one of them being a disruption to the overall healthcare industry. If one test could replace multiple, costly te…
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Having a baseline understanding of each of our individual health needs should be a no-brainer. Yet, America is still mainly practicing a responsive-based medical model vs. a proactive approach. Today’s guest, Donna Edmonds, says: “We should learn how to manage health, and focus on wellness and prevention.” She is the CEO of BRAINBox Solutions Inc. …
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Why aren't Americans benefiting from customized treatment plans utilizing their specific genome types and targeting the unique needs of the problem? Advanced tests are out there but not enough patients are even getting tested, let alone, having the option of the correct tests! Matt Brane helps break down some of the main reasons preventing these ki…
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Economically Improving the Collaboration Between Payers and Providers w/ Dr. Kenneth Schaecher
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Who owns the fiduciary responsibility between insurance and physicians? Could the answer include both? This episode includes a fantastic conversation about the perspective of larger economics within these roles. Today’s guest is Dr. Kenneth Schaecher, the Interim Chief Medical Officer at the University of Utah Health Plan. Not only does he break do…
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Dear listeners, This is a bittersweet moment for us. With this episode, we conclude the Personalized Medicine Podcast series. We would like to thank all of you for staying with us over the last 3 years! This has been an amazing ride and we appreciate your constant support and feedback. We hope you enjoyed listening to this show as much as we enjoye…
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In this episode of the Personalized Medicine Podcast we sat down with Dr. Victor Bustos, the co-founder and COO of Refoxy Pharma, a pharmaceutical company focused on new therapies for age-related diseases. Victor is a molecular biologist by training and dedicated his research career to understanding the biology of aging. In this interview, we discu…
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There are guidelines that will naturally protect with the patient, employer and payor. It is also beneficial as an employer to establish a helpful relationship with their payor in order to meet the specific needs of their employees. Dr. Phillip Smith, Regional Medical Director at Oscar Health, takes a deep dive into the benefits of this type of car…
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What will it take for there to be price transparency for preventative medicine? The No Surprise Bill is a start! There is also the need for consumers to understand their options and for physicians to stay current on the latest technology. This is easier said than done. Today's guest is Dr. Linda Britton, Senior Medical Director, Southeast Region at…
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Ultimately, we want the world to be a better place. Precision Medicine can help with this long-term goal and the labs that are looking to study, test, and prove this kind of work could have incredible opportunities to show up prepared. Continuing our interview with Dr. Carmen Alfonso, who is the Senior Medical Director of Blue Cross Blue Shield Adv…
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Clearly defining the cost structures so that Doctors, Insurance Companies, and patients feel empowered to use personalized medicine to their advantage is what today’s guest believes is one of the best next steps we can take in healthcare. In this Part 1 of 2 interviews, we are joined by Dr. Carmen Alfonso, who is the Senior Medical Director of Blue…
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With the explosion of popularity with personalized medicine in the last decade, the need for clearly defined clinical utility is ever growing. It’s not enough to have the proof that a test works–but what treatment can Doctors and patients then take with those results? This question is explored with today's guest, Dr. Charles Stemple, former Humana …
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Within novel diagnostics tests, needing clinical utility evidence cannot be understated. And the more evidence accumulated over years, the better. But why? Today’s guest is Dr. Virginia Calega, the President of VCC Healthcare Solutions, and she makes a highly compelling argument that, if payors are going to accept a new novel diagnostic test, and d…
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Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana sat down for a conversation with Dr Ali Aghebat Rafat, Scientist at Tilibit Nanosystems. Aradhana and Ali discussed DNA nanostructures, DNA self-assembly, barcoding, biochips and their potential applications in Personalized Medicine. Tune in to this…
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Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana talked to Martin Rabel, the Field Application Scientist at Precision Nanosystems, about nanoparticles, microfluidics, gene delivery in the context of personalized medicine. Tune in to this episode to learn more about: ◦ Precision Nanosystems and the…
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In this episode we dive deep into the world of structural biology. We discuss the role of cryogenic electron microscopy in the development of precision medicines with the founder and CEO of Gandeeva Therapeutics, Dr. Sriram Subramaniam. Cryo-EM opened a new way to study drug-target interactions and is changing the way we develop new therapies. Tune…
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Ep#042: Applying Epigenetics to Personalized Skincare with Dr. Shakiba Kaveh and Dr. Cristiana Banila
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In this next podcast episode we dive into a topic of personalized skincare. Our host Oleksandr is joined by the co-founders of Mitra Bio, Dr. Shakiba Kaveh and Dr. Cristiana Banila. Pharmaceutical and personal care companies have been trying to unlock personalized skincare for decades. Shakiba and Cristiana bring a special key to the table, and it …
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Welcome to the next episode of the Personalized Medicine Podcast. In this episode, we have talked about a variety of topics ranging from exploring space and microgravity for applications in biotechnology and physical science to developing pathogen detection systems. Our guest today is Dr. Daniela Bezdan, the Chief Scientific Officer of Yuri Gravity…
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Ep#040: Eliminating Cancer Using Invariant Natural Killer T Cells (iNKTs) with Dr. Jennifer Buell
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Welcome to the next episode of the Personalized Medicine Podcast. On this podcast we have talked extensively about antibody, vaccine and CAR-T cell based approaches to treat cancer. Today we will be talking about a new approach in oncology that is based on invariant Natural Killer T Cells, or iNKTs. Our guest today is Dr. Jennifer Buell, the founde…
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In this episode we dive deep again into the topic of protein degradation and how it can be leveraged to treat neurodegenerative diseases. Our guest today is Dr. Beth Hoffman, the founder, CEO and President to Origami Therapeutics. Beth's career is a showcase of remarkable success in the biotech industry. She spent almost 25 years working in CNS dru…
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Thank you very much for tuning into this special episode of the Personalized Medicine Podcast. Some of you might know that our founder and host Oleksandr (a.k.a. Sasha) is Ukrainian. In this difficult moment for his country, Sasha shares his thoughts on current situation in Ukraine and explains how anyone in the world can help and support people of…
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In this episode we are returning to a very exciting topic of immunooncology and we will talk in detail about novel approaches to treat cancer, based on CAR-T cell technology. Please welcome Dr. Eric von Hofe, the Senior Advisor and former President of Affyimmune Therapeutics. Eric’s story is a showcase of a remarkable career in the biotech industry…
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Welcome to the next episode of the Personalized Medicine Podcast. On this show we typically talk about science and technology driving the progress in personalized medicine. But the policy side of things and patient access are equally important. We are happy to welcome on our podcast Christopher Wells, the Vice President of Public Affairs at the Per…
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Welcome to Season 3 of the Personalized Medicine Podcast! We hope you all head a good start in 2022 and are ready to dive deep into the world of personalized medicine with us again. In this first episode of Season 3, we address a very important and, frankly speaking, underappreciated topic of sepsis, commonly known as bacterial blood poisoning. Did…
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2021 in Personalized Medicine: Crossover Episode with the Host of the Genetics Podcast, Dr. Patrick Short
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Welcome to the final episode of 2021! This one was long in the making. We are happy to present the crossover episode between the Genetics Podcast and the Personalized Medicine Podcast. In this episode our host Oleksandr (Sasha) Yagensky wraps up 2021 with one and only Patrick Short, the CEO of Sano Genetics and host of the Genetics Podcast. Listen …
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In this episode of the Personalized Medicine Podcast we are returning to the topic of aging. It is our pleasure to introduce to you the co-founder & CEO of Rejuvenate Bio, Daniel Oliver. Dan studied Mechanical Engineering & Business at Caltech and obtained an MBA from Harvard Business School. After completing his studies, Dan has co-founded several…
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This is officially one of the most fun episodes of the Personalized Medicine Podcast. This time we sat down not just with one, but with two amazing guests. Please welcome the co-founders of Ochre Bio, Jack O’Meara and Quin Wills. Together we talked about livers, drug development for metabolic diseases and biotech entrepreneurship. This episode is f…
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In this episode we are focusing on cancer, oncolytic viruses and how investor mindset helps building successful biotech companies. Our guest today is Arthur Kuan, the CEO of CG Oncology. Arthur is a molecular biologist by training. After completing his undergraduate training, Arthur started his career as a venture investor working at several promin…
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In this episode of the Personalized Medicine Podcast we talk about precision oncology with a scientist and serial entrepreneur, Dr. Gang Song. Gang completed his PhD degree in Biochemistry and Molecular Biology at the Shanghai Medical College of Fudan University and then moved to Harvard where he did a PostDoc at the lab of Tim Springer where he wa…
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Ep#030: Using iPSCs to Discover New Therapies for Neurodegenerative Disorders with Professor Evangelos Kiskinis
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On this episode we take a look at the role induced Pluripotent Stem Cells (iPSCs) are playing in drug discovery and development for neurodegenerative diseases. Our host Oleksandr sat down with Professor Evangelos Kiskinis, who is leading his own research group at the Northwestern University in Chicago. Evangelos and his team are leading the way on …
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In this episode, we are diving deep into the world of the non-coding genome and, more specifically, an exciting new class of biomolecules - the long non-coding RNAs (lncRNA). Welcome, Dr. Samir Ounzain, the co-founder and CEO of HAYA Therapeutics. Samir and his startup HAYA are developing first-in-class therapies to target lncRNA responsible for th…
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Ep#028: Applying Laser Physics to Enable Personalized Stem Cell Therapies with Dr. Nabiha Saklayen
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In this Podcast episode we return to the topic of stem cells. We discussed that autologous stem cells can be a powerful therapeutic tool for Parkinson’s disease in our interview with Professor Jeanne Loring. The challenge however is to manufacture those therapies at scale. Our guest on this episode is taking a major step in alleviating this hurdle.…
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This Podcast episode cannot get any closer to what personalized medicine is really about. Welcome Dr. Dan Rhodes, the founder and CEO of Strata Oncology, a leading precision oncology company leveraging state-of-the art genomics tools for more efficient cancer diagnostics and treatment. Dan is a bioinformatician by training and spent his entire care…
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In this episode, we return to our beloved field of proteomics. This time we focus on answering a question on how automation and AI can improve biomarker discovery and ultimately benefit patients. Our guest is Dr. Sophia Doll, co-founder of OmicEra Diagnostics, one of the most exciting startups in the field of proteomics today. Sophia did her Ph.D. …
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Ep#025: Leveraging Real World Data for Effective Treatment of Multiple Sclerosis with Dr. Richard Rudick
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In this episode we talk about multiple sclerosis (MS) and the role personalized medicine and real world data (RWD) are playing in treating this disease effectively. To discuss this topic, we sat down with one of the leading experts in this field - Dr. Rick Rudick. Rick is a neurologist by training and has more than 25 years of experience at Clevela…
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Scientists today still spend an enormous amount of time on physical labor: pipetting, feeding cells, taking microscope images and performing all kinds of other experiments manually. That leaves researchers with a very limited time to do their core activities such as reading, talking to their colleagues and coming up with new hypotheses. Our guest o…
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In this episode of the Personalized Medicine Podcast, we sat down with the guru of bioinformatics, Dr. John Castle. John is a physicist by training who found a passion for answering complex questions in drug development using a data-driven approach. He led bioinformatics teams at multiple successful companies including Rosetta Inpharmatics, Merck a…
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In this episode, our host Aradhana Chopra sat down with Leo Martinez, one of the co-founders of Colorimetrix, the mobile health tech company behind the Pearl Fertility app. It is the first App to be approved as a medical device to monitor and chart all-important hormones of the menstrual cycle at home and help women with their fertility decisions. …
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