))
Welcome to the Precision Medicine Podcast by Trapelo. This is the podcast where experts come to discuss the problems oncologists, reference labs, and payers face as precision medicine grows, and consider solutions for advancing the quality of patient-centered cancer care.
…
continue reading
Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
…
continue reading
Welcome to the “Precision Medicine Made Simple Podcast,” where we simplify the complex world of precision medicine. We're here to explore how personalized healthcare can empower you to understand and improve your health to live a longer and healthier life. Join us as we break down the latest in medical science into actionable insights. Let's make precision medicine accessible and actionable for everyone. Sponsored by: Biography Health, where healthcare meets personalization. With their DNAbl ...
…
continue reading
1
The Pursuit of Precision: The Science Advancing Individualized Medicine
Mayo Clinic Center for Individualized Medicine
This podcast series focuses on in-depth conversations with researchers and physicians on discoveries and emerging science in precision medicine. Each episode features lively discussion between a Mayo Clinic colleague and guest from an external institution. We welcome your questions and comments, please email us at precisionpod@mayo.edu
…
continue reading
1
The view from 30,000: Healthcare & life science AI in the cloud | Talking Precision Medicine #41
37:10
This episode features a conversation with Shweta Maniar, who leads the Healthcare and Life Science effort at Google cloud. In just a few short years, artificial intelligence has gone from the stuff of hype and fairy tale to powerful and ubiquitous tools for all aspects of R&D and healthcare delivery. Google has been central to this sea change. I di…
…
continue reading
Beauty Span and Health Span: Where Aesthetics Meets Longevity with Dr. Cory Goldberg For this episode, we dive deep into the intersection of aesthetics and longevity with Dr. Cory Goldberg, a renowned plastic and craniofacial surgeon. Dr. Goldberg bridges the art of aesthetic medicine with the science of precision medicine, sharing groundbreaking i…
…
continue reading
1
Dr. William Oh on How Precision Medicine and Early Detection Transform Outcomes in Prostate Cancer Care
41:38
In part one of a two-part series on prostate cancer, the Precision Medicine Podcast addresses critical challenges as well as new advancements in prostate cancer, the second leading cause of cancer-related deaths in men. Host, Karan Cushman, is joined by Dr. William Oh, Director of Precision Medicine at Yale Cancer Center and Chair of the American C…
…
continue reading
From Flight Medic to Precision Medicine with Dr. Kat Schmolly In this episode, we're joined by Dr. Kat Schmolly. From her adventurous past as an Air Force Flight Medic to her current mission revolutionizing rare disease diagnosis, Dr. Schmolly shares her unique journey into precision medicine. We discuss why bringing personalized care to the frontl…
…
continue reading
1
A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell Scoles
55:22
A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell Scoles In this episode, we explore pharmacogenomics, also known as genetic pharmaceutical profiling with Dr. Lyndell Scoles with MDVIP. He’s an early pioneer in using genetic testing to optimize medication choices. With over 30 years of experience in interna…
…
continue reading
1
What’s in a digital twin? Inventing new kinds of AI for biomedicine | Talking Precision Medicine #40
47:02
Our guest this episode is Charles Fisher, co-founder and currently Chief Scientific Officer of Unlearn.AI. Unlearn has been a leader in the advancement of Digital Twins as a tool to drastically improve the efficiency of clinical trials. Not only a visionary scientist and trailblazing entrepreneur, Charles is fearless with his hot takes. So sit back…
…
continue reading
Ep. 15 - Beyond One-Size-Fits-All: The Science of Drug-Gene Interactions with Michelle Beckwith This episode features Michelle "Shelly" Beckwith, a genetics pioneer since the 1990s who worked on the Human Genome Project. She breaks down how pharmacogenetic testing helps optimize medication choices by analyzing how patients' genetic variations affec…
…
continue reading
Genotyping vs. Sequencing: What's the Difference? In this episode, Dr. William Stanford, Dr. Yelena Bykhovskaya and Taylor Cu discuss various genetic testing methods. The conversation compares genotyping, exome sequencing, and whole genome sequencing, with an emphasis on whole genome sequencing, which provides the most comprehensive genetic informa…
…
continue reading
1
Leave No Patient Behind—R&D Tools and Cutting Edge Diagnostics that Span the Globe | Talking Precision Medicine #39
35:38
What a genuine pleasure to sit with Thierry Bernard, CEO of Qiagen. As I told Thierry, Qiagen is a truly iconic brand for anyone who came up through molecular biology laboratories in the past 30 years. Their products were ubiquitous, and crucial, to the success of our research. In this conversation, Thierry talks about his global vision for precisi…
…
continue reading
1
Bridging the Gap: Scientists and Physicians in Precision Medicine with Yelena Bykhovskaya, PhD
1:15:41
In this episode, Dr. Yelena Bykhovskaya, Chief Scientific Officer at Biography Health, shares her expertise in genetics. We explore the importance of both polygenic and monogenic risk scores in patient care. The conversation underscores the value of combining cutting-edge genetic analysis with traditional clinical factors in the evolving field of p…
…
continue reading
1
How Doctors are Using Genetic Data to Transform Patient Care with Philip Bretsky MD PhD MPH FACP
58:33
How Doctors are Using Genetic Data to Transform Patient Care with Philip Bretsky MD PhD MPH FACP In this episode, we're joined by Dr. Philip Bretsky, a board-certified internist from Santa Monica with expertise in epidemiology and Alzheimer's research. Dr. Bretsky discusses how precision medicine is transforming healthcare by integrating genetics, …
…
continue reading
1
New Legislation Helps Deliver Appropriate Biomarker Testing to More Cancer Patients When and Where They Need It
37:43
New Legislation Helps Deliver Appropriate Biomarker Testing to More Cancer Patients When and Where They Need It Currently, there is a significant divide between the promise of precision medicine and how equitably new innovations are applied to each cancer patient’s treatment journey. Our expert guests Hilary Gee Goeckner (Director of State and Loca…
…
continue reading
Redefining the Healthcare Model: Insights from 20-Year Executive Lucy Janoyan In this episode, we're joined by special guest Lucy Janoyan, Chief Strategy Officer at Biography Health. With over two decades of healthcare executive experience, Lucy explores the transition from reactive to proactive healthcare. She discusses the challenges facing prima…
…
continue reading
What a pleasure to sit down with my long time colleague and friend, Art Krieg, to discuss his latest venture, Zola Therapeutics, and his adventures in the great outdoors. Art has launched and exited a number of innovative biotechs, each time delving deeper into mechanisms by which we can harness the immune system for therapeutic purposes. Join us a…
…
continue reading
Gen Z Takes Action: The Preventive Health Shift In this episode, we're joined by two younger guests for our Gen Z special featuring Eliana Stanford, Dr. Stanford's daughter, and Lexie Horizon, whose parents are fellow doctors and friends of Dr. Stanford, and who recently interned at Biography Health. This unique conversation explores why younger ge…
…
continue reading
Taylor Can't Outrun His Genetics: Lipid Panel Reality Check In this episode, Dr. Stanford and I uncover surprising truths from my advanced lipid panel. Despite my active lifestyle, the results reveal hidden risks for heart disease and diabetes. We explore how genetic factors and subtle imbalances can impact long-term health, and discuss targeted in…
…
continue reading
In this informative episode of the Precision Medicine Made Simple Podcast, we delve into the world of lipids with Dr. Stanford. Learn what lipids are and why they're crucial for your health, especially regarding heart disease prevention. We explore the differences between HDL and LDL cholesterol, discuss genetic factors influencing lipid levels, an…
…
continue reading
1
Cell therapy for T-cell malignancies—the science and business of developing curative medicines for patients in need | Talking Precision Medicine #37
39:01
In this episode I chat with Dr Sarah Hein, co-founder and CEO of March Biosciences, a Houston Based biotech developing cell therapies for T-cell malignancies. Sarah is an old friend and colleague from our days as trainees at Baylor College of Medicine, where we both circulated among those with ambitions of entrepreneurship. Sarah has definitely mad…
…
continue reading
From Genes to Actions: Taylor's DNAbled Blueprint Experience Today marks the beginning of an ongoing series where I'm pulling back the curtain on my personal journey through the DNAbled Blueprint process. You'll get an exclusive, firsthand look at: My own intake form: Revealing insights from my personal and family health history One of my genetic r…
…
continue reading
Cracked the Genetic Code! Methylation and the Future of Precision Medicine This is the second half of the two part series to Dr. Stanford’s presentation called, “Optimizing Healthspan and Longevity by Implementing Personalized Precision Medicine.” For this episode, we dive into the science of methylation patterns and how we can use it to detect var…
…
continue reading
These next two episodes are a two part series to Dr. Stanford’s presentation called “Optimizing Healthspan and Longevity by Implementing Personalized Precision Medicine. Think of this episode like Precision Medicine 101. Dr. Stanford dives into a number of different topics including the evolution of personalized precision medicine and how its chang…
…
continue reading
Welcome to Part 2 of a two-part colorectal cancer (CRC) awareness series featuring guest Trevor Maxwell, Founder and CEO of Man Up to Cancer, a non-profit that inspires men to connect and avoid isolation during their cancer journeys. Trevor shares what he’s learned since being diagnosed with stage 4 CRC six years ago, the darkness he faced from men…
…
continue reading
For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu discuss the topic of cancer. Dr. Stanford provides a comprehensive breakdown of cancer cells, stressing the need for genetic and molecular profiling to tailor treatments. They explore the factors that contribute to cancer development, including lifestyle choices and genetic mutations, a…
…
continue reading
1
Tackling healthcare disparities and bridging the digital divide: it doesn’t have to be so hard | Talking Precision Medicine #36
44:13
This episode features two guests, Jennifer Goldsack and Yashoda Sharma, of the Digital Medicine Society, or DiMe. We’re going to get into the nitty gritty of healthcare disparities in terms of access and outcomes, and how digital solutions are a big part of the overall solution. Episode 36 links: TPM E36 for highlights and links from this epi…
…
continue reading
For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu dive into the complexities of metabolic syndrome, how it can relate to several chronic diseases and discuss the impact of genetics, diet, and exercise on our overall health. We also touch on the importance of precision medicine and continuous glucose monitoring in managing conditions li…
…
continue reading
In this episode, we’re joined by Dr. Stanford and Taylor Cu to explore neurodegenerative diseases such as Alzheimer’s and Parkinson's. It's a particularly personal discussion as Dr. Stanford shares his own genetic risk for Alzheimer’s, linked to the APOE4 gene. Dr. Stanford explains what neurodegenerative diseases are and dives into the specifics o…
…
continue reading
1
Part 1. The Alarming Rise of Colorectal Cancer: Advocate Trevor Maxwell Explains Why Basic Screening Is Mission Critical
37:55
Today, 80% of adults younger than 60 are not being effectively screened for colorectal cancer. They now have a 50% greater chance of being diagnosed than they did in the 90s. Additionally, the rise of early-onset CRC—even in otherwise healthy young people in their 20s and 30s—is unprecedented. This marks the 60th episode of the Precision Medicine P…
…
continue reading
Dr. Stanford, Alyssa Stanford, and Taylor Cu explore the fascinating world of heart disease and personalized health care. They dive into the complexities of heart disease, discussing the crucial role of genetics, family history, lifestyle, and biochemistry in assessing heart disease risk. Tune in to discover the power of early detection, personaliz…
…
continue reading
In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger, head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies. Episode 35 l…
…
continue reading
In this episode of the Precision Medicine Podcast, host Karan Cushman does some time traveling with Dr. Douglas Flora through his lifetime journey with cancer. Dr. Flora is the Medical Director of Oncology Services at St. Elizabeth Healthcare and Editor-in-Chief AI in Precision Oncology, a peer-reviewed research journal dedicated to advancing artif…
…
continue reading
1
Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34
31:38
Today we turn the mic around, as our guest Adam Stasio hosts an excellent podcast of his own. Adam’s day job, however, is running SciMed, a boutique life sciences software development company. Adam and Genialis CEO Rafael Rosengarten discuss the state of scientific software, the importance of agility and communication, and approaches to building a …
…
continue reading
1
New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33
42:45
Our guest today is Dr. Ashley Zehnder, co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out … Visit…
…
continue reading
1
To achieve personalized medicine, start by getting the dose right | Talking Precision Medicine #32
39:13
In this episode, Genialis CEO Rafael Rosengarten sits down with Ajay Gopal, CEO and founder of Rx Studio. Rx Studio is a technology company using data science to tackle a major limitation to personalized medicine: drug dosing. Visit TPM E32 for highlights and links from this episode.
…
continue reading
What if we could replace diseased or damaged organs and other body parts with new lab-created versions? How might transplanting tissue from other species help the critical shortage of human transplant organs? Tune in to listen to two noted experts in regenerative therapeutics and xenotransplantation (transplanting organs between members of differen…
…
continue reading
In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall. They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List. Visit TPM E31 for highlights and links from this episode.…
…
continue reading
Wearable technology has come a long way from being a novelty. These wearables are now being used to help monitor patients to forestall problems. They can help people take a more active role in their health. Plus, the trove of data they collect can help medical researchers. Explore how wearables and digital health individualize medicine in this epis…
…
continue reading
Wearable technologies are becoming more and more popular. Add to the mix digital health apps and there's a trove of data being translated into meaningful health information for users, physicians and researchers. Explore the emergence of these digital tools in individualized medicine in this episode of Mayo Clinic's "The Pursuit of Precision: The Sc…
…
continue reading
1
People first: building a company that inspires impactful work | Talking Precision Medicine #30
51:06
This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis. The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world. Visit TPM E30 for highlights …
…
continue reading
Organoids are like mini organs giving researchers new insights into human development and disease and could revolutionize fields like drug discovery. Researchers can develop a wide variety of organoids from the liver to the brain. Hear about the potential and limitations of using human organoids to bridge the gap between human and animal research. …
…
continue reading
Dive into how some of the changes in clinical trials can be applied to the stages of the cancer continuum, including cancer prevention, early detection and treatment. Listen to two noted experts discuss how individualized medicine has changed the clinical trials field. Find out more about the next generation of clinical trials researchers are using…
…
continue reading
Find out how 3D printing techniques play a key role in developing tissues that could be implanted into humans. Two noted experts in the field of 3D printing in medicine discuss the technological advancements, in-house printing, reimbursement challenges and applications in surgery to improve patient care. Guests are: Jonathan Morris, M.D., Associate…
…
continue reading
1
Dr. Pranil Chandra and Dr. Luis Raez: Enabling Comprehensive Genomic Profiling in Lung Cancer
46:13
In this episode of the Precision Medicine Podcast, hosts Karan Cushman and Clynt Taylor welcome back Dr. Luis Raez, Medical Director and Chief Scientific Officer at Memorial Cancer Institute who is joined by Dr. Pranil Chandra, Chief Genomic Officer at PathGroup. Together, we discuss the key barriers to performing comprehensive genomic profiling in…
…
continue reading
Some vaccines prevent cancer, while other vaccines treat cancer. Listen to two noted experts in immunology as they discuss the differences between the two vaccines, the excitement and challenges in the precision oncology world on how to design vaccines for individual cancer types, the importance of clinical trials, and advances in immunotherapy. Gu…
…
continue reading
Mayo Clinic offers a rapid genome sequencing test for newborns where they sequence the entire genome of the baby and compare it to the parent’s DNA to identify the causes of severely ill newborn babies. Find out more about this new field of genomic medicine, ethics involved and the potential and hurdles of using genome based newborn screening as st…
…
continue reading
What are the challenges of dealing with viruses like COVID-19? Two infectious disease experts discuss lessons learned in the pandemic, vaccines, and novel therapeutics. Some viruses are easier to defeat with a vaccine and others are not. Learn about new technology to attack emerging viruses, the importance of funding to develop drugs and how resear…
…
continue reading
Did you know that any two human beings are 99.9% identical? Learn more from two experts in population genomics, the large-scale comparison of DNA sequences of populations and how groups are related over time. Understand the drivers of disease and how genetics affects our risks across the population. Discover how researchers are moving population ge…
…
continue reading
In the inaugural podcast episode host Cathy Wurzer, a broadcast journalist from Minnesota Public Radio, talks with two experts in this new frontier of medicine. The exposome looks at everything a person has been exposed to in their lifetime — chemicals, pollution, radiation, biological agents, nutrients in food and measures those exposures to ident…
…
continue reading
Our guest this episode is Dr. Susanna Harris, community lead at Vibe Bio. Susanna is a dedicated scientific communicator and an outspoken advocate for the mental health of PhD students and other science researchers. She has chronicled her journey from the academic lab bench to a venture incubator to a promising biotech company for a substantial soc…
…
continue reading
1
Dr. Debra Patt: Texas Oncology Has an “Easy Button” for Delivering Consistent Precision Oncology Care
26:37
To mark the beginning of Season 5 of the Precision Medicine Podcast, we are honored to welcome Dr. Debra Patt, Executive Vice President of Texas Oncology. As an oncologist and breast cancer specialist at one of the nation’s largest community cancer practices, Dr. Patt is on the frontlines of oncology care every day. She joins us to discuss how Texa…
…
continue reading
1
A new way to finance drug development, for rare disease and beyond | Talking Precision Medicine #28
45:36
In this episode, our host and Genialis CEO Rafael Rosengarten spotlights Vibe Bio. Vibe Bio is a new biotech aiming to disrupt how we finance drug development through stakeholder communities and cryptocurrency, starting in the rare disease arena. Our guest is Alok Tayi, co-founder and CEO of Vibe. Alok is a successful serial entrepreneur and a rare…
…
continue reading
