最佳The Long Run With Luke Timmerman播客 (2025)

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Ep172: Mostafa Ronaghi on Studying Live Cells at Scale 1:20:53

5d ago1:20:53

1:20:53

Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.由Timmerman Report

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Ep171: Ram Aiyar on RNA Editing Medicines 1:01:48

19d ago1:01:48

1:01:48

Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.由Timmerman Report

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Ep170: David Schenkein on Investing in the Future of Biotech 59:52

30d ago59:52

59:52

David Schenkein, general partner at GV, on investing in the future of biotech.由Timmerman Report

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Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines 1:02:28

2M ago1:02:28

1:02:28

Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.由Timmerman Report

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Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer 1:00:23

2M ago1:00:23

1:00:23

Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.由Timmerman Report

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Ep167: Leslie Williams on transfer RNA therapies 1:11:28

3M ago1:11:28

1:11:28

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.由Timmerman Report

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Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity 1:03:35

4M ago1:03:35

1:03:35

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.由Timmerman Report

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Ep165: Zach Hornby on Tackling Cancer Drug Resistance 1:02:45

4M ago1:02:45

1:02:45

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.由Timmerman Report

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Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients 56:39

5M ago56:39

56:39

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.由Timmerman Report

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Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases 1:08:19

6M ago1:08:19

1:08:19

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.由Timmerman Report

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Ep162: Sean McClain on AI for Biologic Drug Discovery 1:05:59

7M ago1:05:59

1:05:59

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.由Timmerman Report

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Ep161: Jeff Stein on a Long-Lasting Flu Drug 1:08:51

7M ago1:08:51

1:08:51

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.由Timmerman Report

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Ep160: Abe Ceesay on Precision Neuroscience 1:08:48

8M ago1:08:48

1:08:48

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.由Timmerman Report

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Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease 1:07:22

8M ago1:07:22

1:07:22

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.由Timmerman Report

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Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery 1:00:44

9M ago1:00:44

1:00:44

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.由Timmerman Report

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Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery 56:33

9M ago56:33

56:33

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.由Timmerman Report

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Ep156: David Liu on New Tools and Techniques for Biology 1:52:57

10M ago1:52:57

1:52:57

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.由Timmerman Report

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Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's 1:02:37

11M ago1:02:37

1:02:37

Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.由Timmerman Report

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Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer 1:03:14

12M ago1:03:14

1:03:14

Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.由Timmerman Report

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Ep153: Rick Young on Studying Gene Expression for Drug Discovery 1:01:43

1y ago1:01:43

1:01:43

Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.由Timmerman Report

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Ep152: Jens Eckstein on Investing in Healthy Aging 1:05:05

1y ago1:05:05

1:05:05

Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.由Timmerman Report

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Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer 1:03:55

1y ago1:03:55

1:03:55

Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.由Timmerman Report

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Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance 1:03:48

1y ago1:03:48

1:03:48

Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.由Timmerman Report

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Ep149: Nancy Stagliano on Precision Neuroscience 1:01:53

1y ago1:01:53

1:01:53

Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.由Timmerman Report

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Ep148: Diana Brainard on the Fight Against Infectious Disease 1:03:27

1y ago1:03:27

1:03:27

Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.由Timmerman Report

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Ep147: Reid Huber on Investing in the Future of Medicine 1:08:41

1y ago1:08:41

1:08:41

Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.由Timmerman Report

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Ep146: Jeff Huber on Life in Tech and Biotech 1:47:05

1+ y ago1:47:05

1:47:05

Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.由Timmerman Report

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Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer 1:06:39

1+ y ago1:06:39

1:06:39

Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.由Timmerman Report

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Ep144: Turning the Tables, Rob Perez Interviews Me 1:04:58

1+ y ago1:04:58

1:04:58

Turning the Tables, Rob Perez Interviews Me由Timmerman Report

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Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders 1:10:25

1+ y ago1:10:25

1:10:25

Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech Founders由Timmerman Report

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Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be 55:54

1+ y ago55:54

55:54

Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.由Timmerman Report

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Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets 1:09:30

1+ y ago1:09:30

1:09:30

Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.由Timmerman Report

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Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas 1:02:40

1+ y ago1:02:40

1:02:40

Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.由Timmerman Report

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Ep139: Kevin Conroy on Early Detection of Cancer 1:08:28

1+ y ago1:08:28

1:08:28

Kevin Conroy, CEO of Exact Sciences, on early detection of cancer.由Timmerman Report

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Ep138: Jodie Morrison on Becoming a Biotech CEO 1:00:17

1+ y ago1:00:17

1:00:17

Jodie Morrison, acting CEO of Q32Bio, on becoming a biotech CEO.由Timmerman Report

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Ep137: Aaron Ring on Immunotherapy for Cancer & More 56:37

1+ y ago56:37

56:37

Aaron Ring, a scientist at Yale moving to the Fred Hutchinson Cancer Center, on applying immunology and protein engineering for cancer therapy and more.由Timmerman Report

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Ep136: Deborah Palestrant on Building Biotech Startups 52:52

1+ y ago52:52

52:52

Deborah Palestrant, partner at 5AM Ventures and head of the 4:59 initiative, on building biotech startups.由Timmerman Report

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Ep135: John Maraganore on Developing a New Class of Medicines 1:03:51

1+ y ago1:03:51

1:03:51

John Maraganore, former founding CEO of Alnylam Pharmaceuticals, on his life in biotech and developing RNA interference as a new class of medicine.由Timmerman Report

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Ep134: Emile Nuwaysir on In Vivo Gene Editing Therapies 1:16:22

2y ago1:16:22

1:16:22

Emile Nuwaysir, CEO of Boston-based Ensoma, on developing off-the-shelf in vivo gene editing therapies.由Timmerman Report

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Ep133: Catherine Stehman-Breen on Epigenetic Editing Therapies 1:10:33

2y ago1:10:33

1:10:33

Catherine Stehman-Breen, CEO of Boston-based Chroma Medicine, on developing epigenetic editing therapies.由Timmerman Report

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Ep132: Eric Dobmeier on Treating Kidney Disease 1:05:44

2y ago1:05:44

1:05:44

Eric Dobmeier, CEO of Seattle-based Chinook Therapeutics, on new strategies for treating kidney diseases.由Timmerman Report

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Ep131: Ryan Watts on Neuroscience Drug R&D 1:05:32

2y ago1:05:32

1:05:32

Ryan Watts, CEO of South San Francisco-based Denali Therapeutics, on neuroscience drug discovery and development.由Timmerman Report

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Ep130: David Hallal on a Life in Biotech & the Cell Therapy Wave 1:09:29

2y ago1:09:29

1:09:29

David Hallal, CEO of ElevateBio, on a long career in biotech and the coming 50-year opportunity in cell therapy and gene therapy.由Timmerman Report

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Ep129: Joanne Smith-Farrell on Engineered B-Cell Therapies 1:11:43

2y ago1:11:43

1:11:43

Joanne Smith-Farrell, CEO of Cambridge, Mass.-based Be Biopharma, on Engineered B-Cell Therapies for Cancer & Rare Diseases.由Timmerman Report

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Ep128: Rick Berke on Building a Biotech Journalism Outlet to Last 1:00:34

2y ago1:00:34

1:00:34

Rick Berke, co-founder and executive editor of STAT, on building a biotech journalism outlet to last.由Timmerman Report

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Ep127: Jeb Keiper on Computational Drug Discovery 1:09:41

2y ago1:09:41

1:09:41

Jeb Keiper, CEO of Nimbus Therapeutics, on computational drug discovery, an unusual business model, and an important new Tyk2 inhibitor for psoriasis and other forms of autoimmunity.由Timmerman Report

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Ep126: DA Wallach on Becoming a Biotech VC 1:11:38

2y ago1:11:38

1:11:38

DA Wallach, founder and general partner of TIME Bioventures, on becoming a biotech venture investor.由Timmerman Report

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Ep125: Barry Greene on a New Drug for Depression 1:04:52

2y ago1:04:52

1:04:52

Barry Greene, CEO of Cambridge, Mass.-based Sage Therapeutics, on plans to introduce a new type of treatment for depression and postpartum depression.由Timmerman Report