))
Study suggests golden years eventually may be more robust
已归档的系列专辑 ("不活跃的收取点" status)
When?
This feed was archived on October 26, 2024 16:05 (
Why? 不活跃的收取点 status. 我们的伺服器已尝试了一段时间，但仍然无法截取有效的播客收取点
What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.
Manage episode 441535611 series 3382310
内容由UF Health提供。所有播客内容（包括剧集、图形和播客描述）均由 UF Health 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品，您可以按照此处概述的流程进行操作https://zh.player.fm/legal。
Imagine yourself old. If you’re already old, just think of yourself as you are now.
But instead of how you feel or expect you would feel, envision older adulthood as a time your joints aren’t complaining. You need no walker because you’re not frail, so you haven’t broken any bones. Your eyesight and hearing? Imperfect, but not terrible.
How would that kind of old age grab you? Not so bad, eh?
A team of London researchers has made a finding they say signals that medicine in the future might keep us healthier as we age.
They recently published a study in which they “switched off” a protein called IL-11 [I-L 11] in mice, extending their healthy lifespan by nearly 25%.
They then treated 75-week-old mice — that’s roughly 55 in human years — by injecting an antibody to thwart IL-11’s effects.
The treatment largely freed the mice from dying of cancer and reduced the many diseases caused by fibrosis, chronic inflammation, and poor metabolism, all sure signs of aging. There were scant side effects.
After about age 55, humans produce more of the IL-11 protein. It’s been linked to muscle wasting, cardiac fibrosis, and frailty, among other things.
In the new study, the mice were given the anti-IL-11 drug from 75 weeks until their death. Males’ lives were extended by 22.4% and female lives by 25%. The mice lived an average 155 weeks, instead of 120.
Research is needed to gauge safety and effectiveness of the anti-IL-11 drugs for humans, of course.
But perhaps as our lifespans grow, more of us will live the adage that it’s not how old you are, it’s how you are, old.
75集单集
分享
