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内容由Karl Klose, PhD and Karl Klose提供。所有播客内容(包括剧集、图形和播客描述)均由 Karl Klose, PhD and Karl Klose 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal
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050: Into the Matrix: Fungal Biofilms with David Andes

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Manage episode 231984049 series 1672442
内容由Karl Klose, PhD and Karl Klose提供。所有播客内容(包括剧集、图形和播客描述)均由 Karl Klose, PhD and Karl Klose 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Candida albicans is the most common fungal infection of humans. C. albicans can cause superficial infections like thrush or vaginitis when it overgrows within healthy individuals, but it causes much more serious disease when it infects immunocompromised individuals. C. albicans can form a matrix-encased biofilm on indwelling medical devices that serves as a source to seed systemic infections in patients.

Dr. David Andes is a professor at the University of Wisconsin and also the chief of Division of Infectious Disease who studies fungal infections.

Dr. Andes talks about the problem of fungal biofilms and antifungal resistance, how the biofilm matrix protects fungi from antifungals, the critical importance of developing new antifungals, and how mixing clinical duties and laboratory research is important for the advancement of fungal treatment.

The microCase for listeners to solve is about Sartha Mewart, a TV and media personality who gets an infection after her stint in prison.

Participants: Karl Klose, Ph.D. (UTSA) David Andes, M.D. (University of Wisconsin) Janakiram Seshu, Ph.D. (UTSA) Jose Lopez-Ribot, Ph.D., Pharm.D. (UTSA) Daniel Montelongo Jaregui (UTSA) Maggie Donohue (UTSA) Katie Quigley (UTSA)

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83集单集

Artwork
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Manage episode 231984049 series 1672442
内容由Karl Klose, PhD and Karl Klose提供。所有播客内容(包括剧集、图形和播客描述)均由 Karl Klose, PhD and Karl Klose 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Candida albicans is the most common fungal infection of humans. C. albicans can cause superficial infections like thrush or vaginitis when it overgrows within healthy individuals, but it causes much more serious disease when it infects immunocompromised individuals. C. albicans can form a matrix-encased biofilm on indwelling medical devices that serves as a source to seed systemic infections in patients.

Dr. David Andes is a professor at the University of Wisconsin and also the chief of Division of Infectious Disease who studies fungal infections.

Dr. Andes talks about the problem of fungal biofilms and antifungal resistance, how the biofilm matrix protects fungi from antifungals, the critical importance of developing new antifungals, and how mixing clinical duties and laboratory research is important for the advancement of fungal treatment.

The microCase for listeners to solve is about Sartha Mewart, a TV and media personality who gets an infection after her stint in prison.

Participants: Karl Klose, Ph.D. (UTSA) David Andes, M.D. (University of Wisconsin) Janakiram Seshu, Ph.D. (UTSA) Jose Lopez-Ribot, Ph.D., Pharm.D. (UTSA) Daniel Montelongo Jaregui (UTSA) Maggie Donohue (UTSA) Katie Quigley (UTSA)

  continue reading

83集单集

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