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Journal Club: Designing Psychedelics Without the Trip
Manage episode 375676850 series 3507121
Join Alaina and Zarmeen as they discuss the paper titled "Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity" by Kaplan et al., 2022. A very topical paper in which researchers identified new drugs based on structural similarities to LSD that are selective at the 5-HT2A receptor. These compounds show promising antidepressant activity in mice, but seem to have no hallucinogenic activity. They discuss the methods, key findings, and takeaways of this incredible paper!
The content of YBOS is the opinion of the authors and does not reflect the opinion of others or author affiliations.
66集单集
Manage episode 375676850 series 3507121
Join Alaina and Zarmeen as they discuss the paper titled "Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity" by Kaplan et al., 2022. A very topical paper in which researchers identified new drugs based on structural similarities to LSD that are selective at the 5-HT2A receptor. These compounds show promising antidepressant activity in mice, but seem to have no hallucinogenic activity. They discuss the methods, key findings, and takeaways of this incredible paper!
The content of YBOS is the opinion of the authors and does not reflect the opinion of others or author affiliations.
66集单集
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