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Getting Ahead of IgAN: A New Treatment Paradigm for Disease Control ft. Dr. Brad Rovin : 1

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Manage episode 407903836 series 3563882
内容由Travere Therapeutics提供。所有播客内容(包括剧集、图形和播客描述)均由 Travere Therapeutics 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Overview:

In this episode of the Rare Kidney Disease Show, Dr. Rovin, Professor of Internal Medicine and Pathology at Ohio State University and chair of the RKD Scientific Network and Podcast, discusses advances in the management of IgAN through a patient case study.

  • “IgAN progresses more often than we thought and progresses even in patients with low levels of proteinuria.”
  • “We continue to strive for greater improvements.”
  • Approaching IgAN with targeted therapies can affect different aspects of IgAN pathogenesis.”

Key Takeaways:

  • Understanding the Underlying IgAN pathophysiology: Highlight the 4-Hit Hypothesis and the intricate disease mechanism (4:27)
  • IgAN Case Study Introduction (6:57)
  • Treatment Initiation (8:26)
  • Management of Progression: Question the outcomes of initial intervention for this patient (9:50)
  • Foundational Therapy: Optimization for improved outcomes (10:24)
  • Maintenance Options: Explore available therapies to sustain treatment effectiveness (11:05)
  • Postulated Algorithm: Discover an algorithm for inflammation management and proteinuria reduction (11:49)
  • Closing Remarks: Gain insight into future episodes (14:10)
  continue reading

3集单集

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icon分享
 
Manage episode 407903836 series 3563882
内容由Travere Therapeutics提供。所有播客内容(包括剧集、图形和播客描述)均由 Travere Therapeutics 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Overview:

In this episode of the Rare Kidney Disease Show, Dr. Rovin, Professor of Internal Medicine and Pathology at Ohio State University and chair of the RKD Scientific Network and Podcast, discusses advances in the management of IgAN through a patient case study.

  • “IgAN progresses more often than we thought and progresses even in patients with low levels of proteinuria.”
  • “We continue to strive for greater improvements.”
  • Approaching IgAN with targeted therapies can affect different aspects of IgAN pathogenesis.”

Key Takeaways:

  • Understanding the Underlying IgAN pathophysiology: Highlight the 4-Hit Hypothesis and the intricate disease mechanism (4:27)
  • IgAN Case Study Introduction (6:57)
  • Treatment Initiation (8:26)
  • Management of Progression: Question the outcomes of initial intervention for this patient (9:50)
  • Foundational Therapy: Optimization for improved outcomes (10:24)
  • Maintenance Options: Explore available therapies to sustain treatment effectiveness (11:05)
  • Postulated Algorithm: Discover an algorithm for inflammation management and proteinuria reduction (11:49)
  • Closing Remarks: Gain insight into future episodes (14:10)
  continue reading

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