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Explorations of Telomere Biology in the Context of Human Aging with Elizabeth Blackburn - Sanford Stem Cell Symposium 2024

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Manage episode 449794795 series 3381199
内容由UCTV提供。所有播客内容(包括剧集、图形和播客描述)均由 UCTV 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal
Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]
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Manage episode 449794795 series 3381199
内容由UCTV提供。所有播客内容(包括剧集、图形和播客描述)均由 UCTV 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal
Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]
  continue reading

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