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Ep. 74: “Dengue Pathogenesis” Featuring Dr. Neelika Malavige
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Guest:
Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and biomarkers. She talks about the disease burden of dengue and her investigations into risk factors for severe disease. She also discusses her research on COVID-19 vaccines and the role of the microbiome in colon cancer, as well as how she’s working to grow research capabilities in Sri Lanka.
Featured Products and Resources:
- Register now for IMMUNOLOGY2024, happening May 3 – 7 in Chicago!
- Enter to win a free lab coat from the new Lab Coats & Life Podcast.
The Immunology Round Up
SOX17 in Colorectal Cancer – Scientists used AKP organoids to demonstrate that SOX17 orchestrates immune evasion in the early steps of colon cancer.
Tregs in Tumor Immunity – Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade.
Astrocytes in Autoimmunity – Researchers identified astrocyte-derived heparin-binding EGF-like growth factor as a potential therapeutic target in multiple sclerosis.
αβ T Cell Development – By studying patients with pre-TCRα deficiency, scientists found that pre-TCRα may not be absolutely required for αβ T cell development in humans.
Image courtesy of Dr. Neelika Malavige
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Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on December 18, 2024 00:38 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 406143724 series 2895470
Guest:
Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and biomarkers. She talks about the disease burden of dengue and her investigations into risk factors for severe disease. She also discusses her research on COVID-19 vaccines and the role of the microbiome in colon cancer, as well as how she’s working to grow research capabilities in Sri Lanka.
Featured Products and Resources:
- Register now for IMMUNOLOGY2024, happening May 3 – 7 in Chicago!
- Enter to win a free lab coat from the new Lab Coats & Life Podcast.
The Immunology Round Up
SOX17 in Colorectal Cancer – Scientists used AKP organoids to demonstrate that SOX17 orchestrates immune evasion in the early steps of colon cancer.
Tregs in Tumor Immunity – Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade.
Astrocytes in Autoimmunity – Researchers identified astrocyte-derived heparin-binding EGF-like growth factor as a potential therapeutic target in multiple sclerosis.
αβ T Cell Development – By studying patients with pre-TCRα deficiency, scientists found that pre-TCRα may not be absolutely required for αβ T cell development in humans.
Image courtesy of Dr. Neelika Malavige
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