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High-fat, high-sugar diet may promote adult acne; and actinic keratosis clearance: A conversation on photodynamic therapy combo

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Manage episode 264748235 series 2356616
内容由MDedge and Medscape Professional Network提供。所有播客内容(包括剧集、图形和播客描述)均由 MDedge and Medscape Professional Network 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Photodynamic therapy (PDT) has become a preferred treatment of field cancerization. Dr. Vincent DeLeo talks to Dr. Martin Miller about results from a split-sided study evaluating the efficacy of CO2 laser ablative fractional resurfacing pretreatment followed by conventional PDT for treatment of actinic keratoses (AKs). They discuss the clinical benefits of PDT for treatment of AKs as well as future directions for this combination therapy for nonmelanoma skin cancers.

* * *

We also bring you the latest in dermatology news and research:

* * *

Key takeaways from this episode:

  • Photodynamic therapy (PDT) provides consistent predictable results and healing periods without variations in response seen with topical therapies.
  • In a split-sided study, pretreatment with CO2 laser ablative fractional resurfacing in combination with conventional PDT showed increased efficacy of AK clearance vs. conventional PDT alone.
  • This combination therapy showed clearance of superficial basal cell carcinoma, but nodular basal cell carcinoma and squamous cell carcinoma in situ persisted at 6 months.
  • Side effects of treatment included hypopigmentation in face and scalp areas on the laser-treated side.
  • Future directions for treatment may include aminolevulinic acid gel 10% with standard PDT as well as combination with a red-light source to achieve deeper penetration into the skin.

Hosts: Nick Andrews, Vincent A. DeLeo, MD (Keck School of Medicine of the University of Southern California, Los Angeles) Guest: Martin B. Miller, MD (University of California, San Francisco)

Disclosures: Dr. DeLeo is a consultant for Estée Lauder. Dr. Miller received grant support and study drug from DUSA Pharmaceuticals Inc.

Show notes by: Alicia Sonners, Melissa Sears

* * *

You can find more of our podcasts at http://www.mdedge.com/podcasts

Email the show: podcasts@mdedge.com

Interact with us on Twitter: @MDedgeDerm

  continue reading

106集单集

Artwork
icon分享
 
Manage episode 264748235 series 2356616
内容由MDedge and Medscape Professional Network提供。所有播客内容(包括剧集、图形和播客描述)均由 MDedge and Medscape Professional Network 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

Photodynamic therapy (PDT) has become a preferred treatment of field cancerization. Dr. Vincent DeLeo talks to Dr. Martin Miller about results from a split-sided study evaluating the efficacy of CO2 laser ablative fractional resurfacing pretreatment followed by conventional PDT for treatment of actinic keratoses (AKs). They discuss the clinical benefits of PDT for treatment of AKs as well as future directions for this combination therapy for nonmelanoma skin cancers.

* * *

We also bring you the latest in dermatology news and research:

* * *

Key takeaways from this episode:

  • Photodynamic therapy (PDT) provides consistent predictable results and healing periods without variations in response seen with topical therapies.
  • In a split-sided study, pretreatment with CO2 laser ablative fractional resurfacing in combination with conventional PDT showed increased efficacy of AK clearance vs. conventional PDT alone.
  • This combination therapy showed clearance of superficial basal cell carcinoma, but nodular basal cell carcinoma and squamous cell carcinoma in situ persisted at 6 months.
  • Side effects of treatment included hypopigmentation in face and scalp areas on the laser-treated side.
  • Future directions for treatment may include aminolevulinic acid gel 10% with standard PDT as well as combination with a red-light source to achieve deeper penetration into the skin.

Hosts: Nick Andrews, Vincent A. DeLeo, MD (Keck School of Medicine of the University of Southern California, Los Angeles) Guest: Martin B. Miller, MD (University of California, San Francisco)

Disclosures: Dr. DeLeo is a consultant for Estée Lauder. Dr. Miller received grant support and study drug from DUSA Pharmaceuticals Inc.

Show notes by: Alicia Sonners, Melissa Sears

* * *

You can find more of our podcasts at http://www.mdedge.com/podcasts

Email the show: podcasts@mdedge.com

Interact with us on Twitter: @MDedgeDerm

  continue reading

106集单集

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