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Inhale, Exhale, Repeat: Understanding COPD

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Manage episode 422848766 series 3555208
内容由ENCORE Research Group提供。所有播客内容(包括剧集、图形和播客描述)均由 ENCORE Research Group 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

In today's episode, we delve into Chronic Obstructive Pulmonary Disease (COPD), a debilitating lung condition affecting millions worldwide. Characterized by obstructed airflow, COPD's symptoms—ranging from persistent cough and phlegm to life-threatening exacerbations—stem from the progressive degradation of lung structure. This disease is exacerbated by factors like smoking, air pollution, and exposure to occupational hazards like dust and chemicals. With a look at the lung's anatomy, from the macroscopic airways down to the microscopic alveoli, we explore how chronic inflammation and emphysema reduce lung function over time, making every breath a challenge. We also cover strategies to mitigate damage and manage symptoms, offering hope for improved quality of life through better disease management and potential advances in medical treatments.
Participate in clinical research!
www.ENCOREdocs.com

Share with a friend. Rate, Review, and Subscribe to the ENCORE Research Group podcast to be notified when new episodes are released.
Follow us on Social Media:
Facebook
Instagram
Twitter
LinkedIn
Tiktok
For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence podcast. www.MedEvidence.com
Thank you for listening!
References:
Adeloye, D., Chua, S., Lee, C., Basquill, C., Papana, A., Theodoratou, E., ... & Global Health Epidemiology Reference Group (GHERG. (2015). Global and regional estimates of COPD prevalence:

Systematic review and meta–analysis. Journal of global health, 5(2). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693508/

Alagha, K., Palot, A., Sofalvi, T., Pahus, L., Gouitaa, M., Tummino, C., ... & Chanez, P. Íp(2014). Long-acting muscarinic receptor antagonists for the treatment of chronic airway diseases. Therapeutic advances in chronic disease, 5(2), 85-98. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926345/

GOLD, 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD). (2023). 2023 Report: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. https://goldcopd.org

Rabe, K. F., Martinez, F. J., Ferguson, G. T., Wang, C., Singh, D., Wedzicha, J. A., ... & Dorinsky, P. (2020). Triple inhaled therapy at two glucocorticoid doses in moderate-to-very-severe COPD. New England Journal of Medicine, 383(1), 35-48. https://www.nejm.org/doi/10.1056/NEJMoa1916046

Suki, B., Stamenovic, D., & Hubmayr, R. (2011). Lung parenchymal mechanics. Comprehensive Physiology, 1(3), 1317. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929318/

CDC & National Center for Health Statistics. (May 2, 2024). Leading causes of death. https://www.cdc.gov/nchs/fastats/leading-causes-of-death.ht

  continue reading

19集单集

Artwork
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Manage episode 422848766 series 3555208
内容由ENCORE Research Group提供。所有播客内容(包括剧集、图形和播客描述)均由 ENCORE Research Group 或其播客平台合作伙伴直接上传和提供。如果您认为有人在未经您许可的情况下使用您的受版权保护的作品,您可以按照此处概述的流程进行操作https://zh.player.fm/legal

In today's episode, we delve into Chronic Obstructive Pulmonary Disease (COPD), a debilitating lung condition affecting millions worldwide. Characterized by obstructed airflow, COPD's symptoms—ranging from persistent cough and phlegm to life-threatening exacerbations—stem from the progressive degradation of lung structure. This disease is exacerbated by factors like smoking, air pollution, and exposure to occupational hazards like dust and chemicals. With a look at the lung's anatomy, from the macroscopic airways down to the microscopic alveoli, we explore how chronic inflammation and emphysema reduce lung function over time, making every breath a challenge. We also cover strategies to mitigate damage and manage symptoms, offering hope for improved quality of life through better disease management and potential advances in medical treatments.
Participate in clinical research!
www.ENCOREdocs.com

Share with a friend. Rate, Review, and Subscribe to the ENCORE Research Group podcast to be notified when new episodes are released.
Follow us on Social Media:
Facebook
Instagram
Twitter
LinkedIn
Tiktok
For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence podcast. www.MedEvidence.com
Thank you for listening!
References:
Adeloye, D., Chua, S., Lee, C., Basquill, C., Papana, A., Theodoratou, E., ... & Global Health Epidemiology Reference Group (GHERG. (2015). Global and regional estimates of COPD prevalence:

Systematic review and meta–analysis. Journal of global health, 5(2). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693508/

Alagha, K., Palot, A., Sofalvi, T., Pahus, L., Gouitaa, M., Tummino, C., ... & Chanez, P. Íp(2014). Long-acting muscarinic receptor antagonists for the treatment of chronic airway diseases. Therapeutic advances in chronic disease, 5(2), 85-98. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926345/

GOLD, 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD). (2023). 2023 Report: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. https://goldcopd.org

Rabe, K. F., Martinez, F. J., Ferguson, G. T., Wang, C., Singh, D., Wedzicha, J. A., ... & Dorinsky, P. (2020). Triple inhaled therapy at two glucocorticoid doses in moderate-to-very-severe COPD. New England Journal of Medicine, 383(1), 35-48. https://www.nejm.org/doi/10.1056/NEJMoa1916046

Suki, B., Stamenovic, D., & Hubmayr, R. (2011). Lung parenchymal mechanics. Comprehensive Physiology, 1(3), 1317. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929318/

CDC & National Center for Health Statistics. (May 2, 2024). Leading causes of death. https://www.cdc.gov/nchs/fastats/leading-causes-of-death.ht

  continue reading

19集单集

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