使用Player FM应用程序离线!
Live at Annual Episode 3: Clinical Trials - Early Drain with Dr Stefan Wolf
Manage episode 374447062 series 1459666
Aneurysmal subarachnoid hemorrhage (SAH) may be complicated by delayed cerebral ischemia, which is a major cause of unfavorable clinical outcome and death in SAH-patients. Delayed cerebral ischemia is presumably related to the development of vasospasm triggered by the presence of blood in the basal cisterns. To date, oral application of the calcium antagonist nimodipine is the only prophylactic treatment for vasospasm recognized under international guidelines.In retrospective trials lumbar drainage of cerebrospinal fluid has been shown to be a safe and feasible measure to remove the blood from the basal cisterns and decrease the incidence of delayed cerebral ischemia and vasospasm in the respective study populations. However, the efficacy of lumbar drainage had not been evaluated prospectively in a randomized controlled trial until Dr Stefan Wolf and his colleagues at Charité – Universitätsmedizin in Berlin conducted their study. Dr Wolf joins Dr Nick Morris to discuss the study's results.
.
102集单集
Manage episode 374447062 series 1459666
Aneurysmal subarachnoid hemorrhage (SAH) may be complicated by delayed cerebral ischemia, which is a major cause of unfavorable clinical outcome and death in SAH-patients. Delayed cerebral ischemia is presumably related to the development of vasospasm triggered by the presence of blood in the basal cisterns. To date, oral application of the calcium antagonist nimodipine is the only prophylactic treatment for vasospasm recognized under international guidelines.In retrospective trials lumbar drainage of cerebrospinal fluid has been shown to be a safe and feasible measure to remove the blood from the basal cisterns and decrease the incidence of delayed cerebral ischemia and vasospasm in the respective study populations. However, the efficacy of lumbar drainage had not been evaluated prospectively in a randomized controlled trial until Dr Stefan Wolf and his colleagues at Charité – Universitätsmedizin in Berlin conducted their study. Dr Wolf joins Dr Nick Morris to discuss the study's results.
.
102集单集
すべてのエピソード
×欢迎使用Player FM
Player FM正在网上搜索高质量的播客,以便您现在享受。它是最好的播客应用程序,适用于安卓、iPhone和网络。注册以跨设备同步订阅。