February: Pharamcogenetic profiling in children with medical complexity

Pediatric Research Podcast

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2y ago 12:42

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Children with medical complexity typically require multiple medications throughout the course of their treatment. These individuals also increasingly undergo genome-wide testing early in life as a diagnostic test.

Since many medications prescribed to children have established gene-drug interactions, could this genetic data be repurposed to aid precision prescribing in this priority pediatric population?

In today's Pediapod, we meet Early Career Investigator, Gregory Costain, a physician scientist at The Hospital for Sick Children in Toronto, Canada who recently published a retrospective study which looked at this question.

Read the full study here: https://www.nature.com/articles/s41390-022-02313-3

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