Clinically Relevance - Looking at Recent Research (11)
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Manage episode 291143251 series 2818489
Clinical trials and research should always aim to provide information that is meaningful and relevant for patients.
- However, researchers are rarely addressing that topic when presenting results from trials.
- In this episode, we look at published papers from high-ranking journals to get a sense of the extent of that problem.
- You may be surprised by our findings...
We want to make it mandatory to state the researchers' clinical relevance levels ahead of the trial, mentioning what they will consider clinically relevant when they pre-register their research on the clinicaltrials.gov website or similar websites. They then need to compare their findings in both the paper and abstract when publishing data from the study. #clinicalrelevance
LINKS:
Our specific page on our website about requesting clinical relevance statement and evaluation https://www.precision-evidence.com/p/clinical-relevance/
Overview of clinical trials registers like clinicaltrials.gov: https://sites.google.com/a/york.ac.uk/yhectrialsregisters/home/clinicaltrials
Precision Evidence episode 10: “How to Get to Clinically Relevant Research” https://www.precision-evidence.com/10
NOTES:
- Statistical significance vs. clinical significance in clinical research
- Clinical significance, clinical relevance, clinical meaningfulness, clinical evidence
- Why researchers in the clinical field should always note ahead of starting a trial what they would consider clinically relevant and then refer back to that in the paper and abstract
- Looking at 44 papers published in early 2021 in high ranking journals and analyzing the mentioning of clinical relevance
- It is disappointing....
- ALWAYS ASK FOR A CLINICAL RELEVANCE EVALUATION OF THE RESULTS - every time, all of us, whatever relation we have to produce, read and use information from clinical research
- ASK FOR A CLINICAL RELEVANCE EVALUATION OF THE RESULTS - and let's make it just as normal as the p-value #doesitmatter
GET THE ABSTRACT SCREENING TOOL
It can be a challenge to screen papers for clinical relevance. As we go beyond the abstract in this podcast, we have created a screening tool to use when reading an abstract from a clinical research paper.
Using that tool enables you to quickly screen an abstract from a medical journal for clinical relevance selecting only those you want to read. At the same time, you will know why you skipped the rest. Get it at our website https://www.precision-evidence.com
Contact us at email: podcast@precision-evidence.com,
Twitter @PrecisionEBM,
You can learn more at our website, where you can also leave us a voice message.
Website: www.precision-evidence.com
Get the Precision Evidence Newsletter https://bit.ly/3tLBx3Z
Hosts:
Dr. Kim Kristiansen, M.D: @KKristiansenMD
JG Staal: @HealthyEvidence
Music thanks to mixkit.co
13集单集