Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 27

Dr. M's Women and Children First Podcast

Klotho Part I Ok, it is time for a potential log step shift in the human understanding of neurological decline with age starting from birth. Enter the peptide, (C)Klotho, named after the greek goddess of fate who spins the thread of life for all. The Klotho protein was discovered by researchers looking at mice that aged faster than the general mouse population. These mice were noted to have a shortened lifespan, stunted growth, renal disease, blood vessel calcification, cardiac hypertrophy, hypertension, pulmonary disease, cognitive impairment, multi-organ atrophy and fibrosis. (Prud'homme et. al. 2022) When they looked closer, these mice were found to have hypoactive klotho proteins leading to an explosion of research over the past two decades to understand why. The next question was, could the hyperactive state provide an anti aging effect? The answer was a resounding yes! and a discussion on fast food. Enjoy, Dr. M